01Epidemiology | Inverse problems
Recovering the reproduction number from hospital admissions
Observed · admissions
Recovered · transmission
- Question
- How much of an epidemic's transmission history can be recovered from hospital admissions alone?
- Method
- A SIRS compartmental model with piecewise-constant transmission, fitted to 1,495 days of Dutch COVID-19 hospital admissions. The recovered reproduction number is then compared with RIVM's independently published estimate, which the model never sees during fitting.
- Result
- At the model's 21-day resolution, the recovered reproduction number correlates 0.804 with RIVM and agrees on the direction of change 81.5% of the time. More flexibility improves the fit to admissions but eventually makes the hidden transmission path worse: the AIC-selected 219-parameter model falls to 0.173 daily correlation.
- Artifacts
2026 · Written in English
